Rapid Progression of Angioimmunoblastic T Cell Lymphoma Following BNT162b2 mRNA Vaccine Booster Shot: A Case Report
Serge Goldman, Dominique Bron, Thomas Tousseyn, Irina Vierasu, Laurent Dewispelaere, Pierre Heimann, Elie Cogan, Michel Goldman
Abstract
Since nucleoside-modified mRNA vaccines strongly activate T follicular helper cells, it is important to explore the possible impact of approved SARS-CoV-2 mRNA vaccines on neoplasms affecting this cell type. Herein, we report and discuss unexpected rapid progression of lymphomatous lesions after administration of a BNT162b2 mRNA vaccine booster in a man recently diagnosed with AITL.
Topics & Concepts
Booster (rocketry)MedicineMessenger RNABooster doseLymphomaCancer researchVirologyImmunologyVirusBiologyGeneTiterAstronomyBiochemistryPhysicsLymphadenopathy Diagnosis and AnalysisLymphoma Diagnosis and TreatmentCutaneous lymphoproliferative disorders research