Pulmonary aspergillosis and cryptococcosis as a complication of COVID-19
Edward C Traver, Melanie Malavé Sánchez
Abstract
Invasive fungal infections may complicate infection by SARS-CoV-2 and increase morbidity and mortality. A 59-year-old man with multiple medical comorbidities was transferred to our hospital for worsening hypoxic respiratory failure due to COVID-19 and received high-dose corticosteroids and 2 doses of cyclophosphamide. He was diagnosed with pulmonary aspergillosis and cryptococcosis by culture of a bronchoalveolar lavage sample. This patient's secondary infections were likely due to treatment with immunosuppressants, his comorbidities, and his prolonged critical illness.
Topics & Concepts
MedicineBronchoalveolar lavageCryptococcosisAspergillosisComplicationCyclophosphamideFluconazolePulmonary aspergillosisRespiratory failureCoronavirus disease 2019 (COVID-19)MycosisInternal medicineIntensive care medicineImmunologyDermatologyAntifungalLungChemotherapyInfectious disease (medical specialty)DiseaseAntifungal resistance and susceptibilityFungal Infections and StudiesNeutropenia and Cancer Infections