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Design and synthesis of novel indole and indazole-piperazine pyrimidine derivatives with anti-inflammatory and neuroprotective activities for ischemic stroke treatment

Hongwei Wang, Enjing Cui, Jiaming Li, Xiaodong Ma, Xueyang Jiang, Shuaishuai Du, Shihu Qian, Le Du

2022European Journal of Medicinal Chemistry40 citationsDOIOpen Access PDF

Topics & Concepts

NeuroprotectionChemistryNeuroinflammationPharmacologyMicrogliaNitric oxideInflammationImmunologyMedicineOrganic chemistryNeuroinflammation and Neurodegeneration MechanismsImmune cells in cancerImmune Response and Inflammation
Design and synthesis of novel indole and indazole-piperazine pyrimidine derivatives with anti-inflammatory and neuroprotective activities for ischemic stroke treatment | Litcius