Acoustic particle trapping driven by axial primary radiation force in shaped traps
L. Malik, A. Nath, Subhajit Nandy, Thomas Laurell, A. K. Sen
Abstract
We study particle trapping driven by the axial primary radiation force (A-PRF) in shaped traps exposed to standing bulk acoustic waves (S-BAW) using numerical simulations and experiments. The utilization of the stronger A-PRF as the main retention force is a consequence of standing-wave formation along the flow direction, instead of the orthogonal direction as in the case of traditionally used lateral-PRF S-BAW trapping setups. The study of particle dynamics reveals that the competition between A-PRF and viscous drag force governs particle trajectory. The ratio of the acoustic energy to the viscous work (β) provides a general criterion for particle trapping at a distinctive off-node site that is spatially controllable. Particles get trapped for β≥β_{cr} at some distance away from the nodal plane and the distance varies as β^{-c} (c=0.6-1.0). The use of A-PRF as the retention force could potentially allow traditional S-BAW trapping systems to envisage high-throughput advancements surpassing the current standards in cell-handling unit operations.