Rational Design of Flavonoid Production Routes Using Combinatorial and Precursor-Directed Biosynthesis
Johann E. Kufs, Sandra Hoefgen, Julia Rautschek, Alexander U. Bissell, Carola Graf, Jonas Fiedler, Daniel Braga, Lars Regestein, Miriam A. Rosenbaum, Julian Thiele, Vito Valiante
Abstract
expression system that can be further exploited to heterologously express pathways not necessarily related to plant polyketide synthases.
Topics & Concepts
Synthetic biologyBiosynthesisBiochemistryComputational biologyPolyketideMetabolic engineeringRational designEnzymeBiologyChemistryCombinatorial chemistryGeneticsMicrobial Natural Products and BiosynthesisPlant biochemistry and biosynthesisMicrobial Metabolism and Applications