Ru(<scp>ii</scp>) photosensitizers competent for hypoxic cancers <i>via</i> green light activation
Francisco J. Ballester, Enrique Ortega, Delia Bautista, M. Dolores Santana, José Ruiz
Abstract
Ru(<sc>ii</sc>) complexes exhibit phototherapeutic indexes higher than 750 in cancer HeLa cells with low nanomolar IC<sub>50</sub> values under low doses of non-harmful green light and are active in normoxia and hypoxia conditions.
Topics & Concepts
HeLaChemistryHypoxia (environmental)Cancer researchBiophysicsBiochemistryMedicineOxygenBiologyIn vitroOrganic chemistryNanoplatforms for cancer theranosticsLuminescence and Fluorescent MaterialsNanocluster Synthesis and Applications