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Reference-guided metagenomics reveals genome-level evidence of potential microbial transmission from the ISS environment to an astronaut's microbiome

Michael Lee, Aubrie O’Rourke, Hernán Lorenzi, Brad M. Bebout, Christopher L. Dupont, R. Craig Everroad

2021iScience18 citationsDOIOpen Access PDF

Abstract

population colonized the astronaut's nasal microbiome while the astronaut was aboard the ISS or that it may have been below detection before spaceflight, instead supporting a shift in community composition. This work highlights the value in generating genomic libraries of microbes from built-environments such as the ISS and demonstrates one way such data can be integrated with metagenomics to facilitate the tracking and monitoring of astronaut microbiomes and health.

Topics & Concepts

MetagenomicsMicrobiomeComputational biologyGenomeBiologyBioinformaticsGeneticsGeneSpaceflight effects on biologySpace Exploration and TechnologyPolar Research and Ecology