A three-component difunctionalization of <i>N</i>-alkenyl amides <i>via</i> organophotoredox radical-polar crossover
Roshan K. Dhungana, Albert Granados, Mohammed Sharique, Jadab Majhi, Gary A. Molander
Abstract
Herein, we report a three-component organophotoredox coupling of N -alkenyl amides with α-bromocarbonyls and various nucleophiles.
Topics & Concepts
ChemistryNucleophilePolarCrossoverComponent (thermodynamics)Medicinal chemistryCombinatorial chemistryStereochemistryOrganic chemistryCatalysisThermodynamicsAstronomyComputer scienceArtificial intelligencePhysicsRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsFluorine in Organic Chemistry