Litcius/Paper detail

Unlocking the potential of engineered immune cell therapy for solid tumors

Víctor Albarrán, Laura Angelats, Julio Delgado, Alena Gros, Álvaro Urbano-Ispizúa, Sònia Guedan, Aleix Prat

2025Nature Communications27 citationsDOIOpen Access PDF

Abstract

Adoptive cell therapy has emerged as a promising approach for treating advanced solid malignancies. Genetic engineering techniques represent an exciting area of research for the development of cellular products with enhanced cytotoxicity, phenotype, and metabolism.

Topics & Concepts

Immune systemCell therapyCellCancer researchMedicineComputational biologyImmunologyChemistryBiologyBiochemistryCAR-T cell therapy researchImmunotherapy and Immune ResponsesCancer Research and Treatments