Litcius/Paper detail

Albumin and fibrinogen synthesis rates in advanced chronic liver disease

Mariam Amouzandeh, Anna Sundström, Staffan Wåhlin, Jan Wernerman, Olav Rooyackers, Åke Norberg

2023American Journal of Physiology-Gastrointestinal and Liver Physiology12 citationsDOI

Abstract

Albumin and fibrinogen synthesis were positively correlated, but the high variation indicates that these are probably influenced by different mechanisms. There might be a limited metabolic reserve for the liver to increase both albumin and fibrinogen synthesis in response to longstanding inflammation in CLD and fibrinogen seems to be prioritized.

Topics & Concepts

FibrinogenAlbuminInternal medicineLiver diseaseMedicineEndocrinologySerum albuminChronic liver diseaseLiver functionChemistryImmunologyCirrhosisLiver Disease Diagnosis and TreatmentLiver Disease and TransplantationNutrition and Health in Aging