Ex vivo expansion of regulatory T cells from long-term Belatacept-treated kidney transplant patients restores their phenotype and suppressive function but not their FOXP3 TSDR demethylation status
Ana Karen Cortés-Hernández, Evelyn Katy Alvarez-Salazar, Saúl Arteaga-Cruz, Josefina Alberú, Gloria Soldevila
Topics & Concepts
BelataceptFOXP3ImmunosuppressionIL-2 receptorImmunologyIn vivoEx vivoKidney transplantationMedicineTransplantationBiologyInternal medicineImmune systemT cellKidney transplantBiotechnologyImmune Cell Function and InteractionT-cell and B-cell ImmunologyRenal Transplantation Outcomes and Treatments