The p75 neurotrophin receptor inhibitor, LM11A-31, ameliorates acute stroke injury and modulates astrocytic proNGF
Sanaz Nasoohi, Pargol Tayefeh Ghahremani, Parsa Alehossein, Siyamak Elyasizadeh, Soha BaniArdalan, Saifudeen Ismael, Hossein Vatanpour, Abolhassan Ahmadiani, Tauheed Ishrat
Topics & Concepts
Low-affinity nerve growth factor receptorNeurotrophinNerve growth factorDownregulation and upregulationMicrogliaMedicineNeurotrophin-3Neurotrophic factorsStroke (engine)Internal medicineBrain-derived neurotrophic factorReceptorInflammationChemistryBiochemistryMechanical engineeringGeneEngineeringNerve injury and regenerationNeuroinflammation and Neurodegeneration MechanismsSignaling Pathways in Disease