In cardiac muscle cells, both adrenergic agonists and antagonists induce reactive oxygen species from NOX2 but mutually attenuate each other's effects
Anamika Prasad, Amena Mahmood, Richa Gupta, Padmini Bisoyi, Nikhat Saleem, Sathyamangla V Naga Prasad, Shyamal K. Goswami
Topics & Concepts
Reactive oxygen speciesPharmacologyMyocyteAntagonistAgonistNADPH oxidaseChemistrySignal transductionSuperoxideMAPK/ERK pathwayBiologyReceptorInternal medicineCell biologyBiochemistryMedicineEnzymeReceptor Mechanisms and SignalingNitric Oxide and Endothelin EffectsCardiac Ischemia and Reperfusion