Preclinical evaluation of KH631, a novel rAAV8 gene therapy product for neovascular age-related macular degeneration
Ke Xiao, Hao Jiang, Qingwei Li, Shuang Luo, Yingfei Qin, Jing Li, Qing Xie, Qiang Zheng
Topics & Concepts
Macular degenerationChoroidal neovascularizationMedicineRanibizumabVascular endothelial growth factorGenetic enhancementTransgeneIntravitreal administrationAdeno-associated virusNeovascularizationRetinaOphthalmologyRegimenRetinalCancer researchRecombinant DNAChemotherapyBevacizumabSurgeryAngiogenesisBiologyGeneVEGF receptorsVector (molecular biology)NeuroscienceBiochemistryRetinal Diseases and TreatmentsRetinal Development and DisordersRetinal and Optic Conditions