Expression, regulation and function of Aquaporin-3 in colonic epithelial cells
Jonathan Yde, Stephen J. Keely, Hanne B. Moeller
Abstract
transporting channel expressed in colonic epithelia. Although expression of colonic epithelial AQP3 is altered in several intestinal disorders, such as inflammatory bowel disease and irritable bowel syndrome, the regulation and specific roles of AQP3 remain to be fully defined. In this mini-review, we summarize the current understanding of the expression, regulation, and biological functions of AQP3 protein in colonic epithelia concerning intestinal absorption, secretion and barrier function.
Topics & Concepts
AquaporinFunction (biology)Cell biologyAquaporin 3EpitheliumAquaporin 2Expression (computer science)Aquaporin 1ChemistryBiologyPathologyMedicineWater channelComputer scienceEngineeringInletProgramming languageMechanical engineeringIon Transport and Channel RegulationElectrolyte and hormonal disordersDiet, Metabolism, and Disease