Direct C–H aminocarbonylation of<i>N</i>-heteroarenes with isocyanides under transition metal-free conditions
Zhong Yuan Zhou, Huihui Ji, Qing Li, Qian Zhang, Dong Li
Abstract
A C–C bond forming amide synthesis through direct C–H aminocarbonylation of<italic>N</italic>-heteroarenes with isocyanides was developed. The reaction was mediated by an inorganic persulfate salt under transition metal-free conditions.
Topics & Concepts
ChemistryAmideTransition metalPersulfateAtom economyCombinatorial chemistrySubstrate (aquarium)Salt (chemistry)StereochemistryMedicinal chemistryOrganic chemistryCatalysisOceanographyGeologySulfur-Based Synthesis TechniquesCatalytic C–H Functionalization MethodsChemical Synthesis and Reactions