Drug–polymer conjugates with dynamic cloud point temperatures based on poly(2-oxazoline) copolymers
Jong‐Ryul Park, Mariah Sarwat, Eleonore C. L. Bolle, Melody A. de Laat, Joachim F. R. Van Guyse, Annelore Podevyn, Richard Hoogenboom, Tim R. Dargaville
Abstract
A shift in cloud point temperatures of poly(2-oxazoline)/ACE inhibitor polymer drug conjugates occurs on release of the drug.
Topics & Concepts
Cloud pointCopolymerConjugateOxazolinePolymerDrugChemistryPolymer chemistryMaterials scienceChemical engineeringOrganic chemistryPharmacologyAqueous solutionMedicineMathematical analysisEngineeringCatalysisMathematicsAdvanced Polymer Synthesis and CharacterizationSynthesis and properties of polymersbiodegradable polymer synthesis and properties