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Nicotine exposure in adolescence triggers the activation and subsequent damage of microglia in the dentate gyrus and promotes depression later in life

Yunli Fang, Rongrong Yang, Rongrong Song, Yiming Gu, Xu Lu, Zhuo Chen, Wenfeng Hu, Ziwei Cao, Micona Sun, Hanxiao Wang, Lijuan Tong, Chao Huang

2025International Immunopharmacology14 citationsDOI

Topics & Concepts

Dentate gyrusMicrogliaNicotineNeurogenesisHippocampal formationHippocampusNeuroscienceAnxiolyticPsychologyMedicineInternal medicineInflammationReceptorNeuroinflammation and Neurodegeneration MechanismsTryptophan and brain disordersNeurogenesis and neuroplasticity mechanisms
Nicotine exposure in adolescence triggers the activation and subsequent damage of microglia in the dentate gyrus and promotes depression later in life | Litcius