Litcius/Paper detail

Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing

Andrew V. Anzalone, Xin D. Gao, Christopher J. Podracky, Andrew T. Nelson, Luke W. Koblan, Aditya Raguram, Jonathan M. Levy, Jaron A. M. Mercer, David Liu

2021Nature Biotechnology576 citationsDOIOpen Access PDF

Topics & Concepts

Prime (order theory)Genome editingGeneticsComputational biologyComputer scienceBiologyParallel computingMathematicsCombinatoricsGenomeGeneCRISPR and Genetic EngineeringChromosomal and Genetic VariationsAdvanced biosensing and bioanalysis techniques