The effects of metal cofactors on the reactivity of quercetin 2,4-dioxygenase: synthetic model studies with M(<scp>ii</scp>)-complexes (M = Mn, Co, Ni, Cu, Zn) and assessment of the regulatory factors in catalytic efficacy
Nirmalya Podder, Sukanta Mandal
Abstract
This paper demonstrates the metal ion effects on the dioxygenation of flavonol catalysed by M( ii )-complexes (M = Mn, Co, Ni, Cu, Zn) as functional models of quercetin 2,4-dioxygenase-like reactivity.
Topics & Concepts
ChemistryReactivity (psychology)MetalLigand (biochemistry)AdductStereochemistryMedicinal chemistryDimethylformamideMetal ions in aqueous solutionSubstrate (aquarium)DioxygenaseEnzymeOrganic chemistryGeologyAlternative medicineOceanographyPathologySolventReceptorBiochemistryMedicineMetal-Catalyzed Oxygenation MechanismsMetal complexes synthesis and propertiesMicrobial metabolism and enzyme function