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Ceramide synthase 6 induces mitochondrial dysfunction and apoptosis in hemin-treated neurons by impairing mitophagy through interacting with sequestosome 1

Aoqian Xu, Yikui Liu, Baofeng Wang, Qixiang Zhang, Yuxiao Ma, Yuxiao Xue, Zhuohang Wang, Qingfang Sun, Yuhao Sun, Liuguan Bian

2024Free Radical Biology and Medicine8 citationsDOI

Topics & Concepts

MitophagyCeramideSequestosome 1Cell biologyApoptosisBiologyMitochondrionGene knockdownCeramide synthaseHeminAutophagyBiochemistryEnzymeHemeAutophagy in Disease and TherapyIntracerebral and Subarachnoid Hemorrhage ResearchSphingolipid Metabolism and Signaling
Ceramide synthase 6 induces mitochondrial dysfunction and apoptosis in hemin-treated neurons by impairing mitophagy through interacting with sequestosome 1 | Litcius