Phase I/IIa Trial of BMS-986148, an Anti-mesothelin Antibody-drug Conjugate, Alone or in Combination with Nivolumab in Patients with Advanced Solid Tumors
Sylvie Rottey, Jeffrey Clarke, Kyaw Aung, Jean‐Pascal Machiels, Ben Markman, Kimberley M. Heinhuis, Michael Millward, Martijn P. Lolkema, Sandip Pravin Patel, Paul de Souza, Matteo Duca, Giuseppe Curigliano, Armando Santoro, Takafumi Koyama, Michelle Brown, Heather Vezina, Chunsheng He, Quincy S. Chu
Abstract
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Topics & Concepts
TolerabilityNivolumabMedicineAdverse effectInternal medicineDosingPhases of clinical researchPharmacologyGastroenterologyMesothelinPharmacodynamicsOncologyClinical trialCancerPharmacokineticsImmunotherapyCAR-T cell therapy researchColorectal Cancer Treatments and StudiesHER2/EGFR in Cancer Research