TnpB homologues exapted from transposons are RNA-guided transcription factors
Tanner Wiegand, Florian T. Hoffmann, Matt W.G. Walker, Stephen Tang, Egill Richard, Hoang C. Le, Chance Meers, Samuel H. Sternberg
Topics & Concepts
BiologyCRISPRGeneticsTransposable elementGeneGenomeComputational biologyTranscription (linguistics)Trans-activating crRNARNACas9PhilosophyLinguisticsCRISPR and Genetic EngineeringBacterial Genetics and BiotechnologyBacteriophages and microbial interactions