Targeted delivery of polo-like kinase 1 siRNA nanoparticles using an EGFR-PEG bispecific antibody inhibits proliferation of high-risk neuroblastoma.
Amy Logan, Christopher B. Howard, Pie Huda, Kathleen Kimpton, Zerong Ma, Kristofer J. Thurecht, Joshua A. McCarroll, Ernest Moles, Maria Kavallaris
Topics & Concepts
NeuroblastomaSmall interfering RNAPLK1Cancer researchEpidermal growth factor receptorRNA interferenceChemistryGene silencingPEG ratioKinaseCellCell cycleCell cultureBiologyReceptorRNABiochemistryFinanceGeneticsEconomicsGeneNeuroblastoma Research and TreatmentsATP Synthase and ATPases ResearchVirus-based gene therapy research