A bioinspired porous and electroactive reduced graphene oxide hydrogel based biosensing platform for efficient detection of tumor necrosis factor-α
Parth Kapil, Damini Verma, Rangadhar Pradhan, Ashish Kalkal, P. Gopinath
Abstract
carried out with differential pulse voltammetry (DPV) technique. Moreover, it exhibits specificity towards TNF-α, even in the presence of potential interferents and other cancer biomarkers. Besides, the biosensor showed good reproducibility and repeatability with a relative standard deviation (%RSD) of 5.11% and 1.85%, respectively. Thus, integrating the L-cys_rGO hydrogel in the immunosensor design offers enhanced performance, paving the way for its application in early-stage oral cancer diagnosis.
Topics & Concepts
GrapheneMaterials scienceBiosensorNanotechnologyPorosityOxideTumor necrosis factor alphaComposite materialMedicineInternal medicineMetallurgyAdvanced biosensing and bioanalysis techniquesElectrochemical sensors and biosensorsGraphene and Nanomaterials Applications