A Synthetic Cumate-Inducible Promoter for Graded and Homogenous Gene Expression in Pseudomonas aeruginosa
Alexander Klotz, Andreas Kaczmarczyk, Urs Jenal
Abstract
. Because this synthetic approach to constructing species-specific inducible promoters is portable, it can serve as a blueprint for similar tailored gene expression systems in bacteria largely lacking such tools, including, for example, representatives of the human microbiota.
Topics & Concepts
Pseudomonas aeruginosaPromoterBiologyGeneGeneticsGene expressionOpportunistic pathogenRegulation of gene expressionComputational biologyMicrobiologyBacteriaBacterial Genetics and BiotechnologyBacterial biofilms and quorum sensingBacteriophages and microbial interactions