Long-term outcomes of patients with preeclampsia, a review of the literature
Alice Tassi, Alessia Sala, Ilaria Mazzera, Stefano Restaino, Giuseppe Vizzielli, Lorenza Driul
Abstract
Hypertensive pregnancy disorders affect up to 10% of all pregnancies and are associated with an increased future risk of heart disease, chronic hypertension, kidney dysfunction, diabetes, and thromboembolism. Although mechanisms are not yet well understood, endothelial dysfunction, pro-inflammatory and procoagulant states seem to persist in women with a history of preeclampsia many years after a pregnancy complicated by HDP. Moreover, the number and severity of these complications differs according to the type of disorder developed during pregnancy. Lifestyle modifications and long-term follow-up are essential to reduce the risk of developing a disease later in life. [Figure: see text].