Synthesis and Anticancer Evaluation of Novel Indole Based Arylsulfonylhydrazides against Human Breast Cancer Cells
Aysha Gaur, Mudasir Nabi Peerzada, Nashrah Sharif Khan, Imran Ali, Amir Azam
Abstract
was found to be nontoxic against HEK 293 noncancerous cells in the studied concentration range, therefore indicating that such chemotypes inhibit the proliferation of cancerous cells selectively and significantly.
Topics & Concepts
MorpholineIndole testChemistryIn vitroCancer cellBreast cancerCell cultureStereochemistryTriple-negative breast cancerIC50MCF-7Estrogen receptorCancerHuman breastBiochemistryBiologyMedicinal chemistryGeneticsSynthesis and biological activitySynthesis and Biological EvaluationMulticomponent Synthesis of Heterocycles