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Human amyloid beta and α-synuclein co-expression in neurons impair behavior and recapitulate features for Lewy body dementia in Caenorhabditis elegans

Xiaobing Huang, Changliang Wang, Liang Chen, Tianjiao Zhang, Ka Lai Leung, Garry Wong

2021Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease23 citationsDOI

Topics & Concepts

Dementia with Lewy bodiesLewy bodyBiologyCaenorhabditis elegansParkinson's diseaseAlpha-synucleinNeuroscienceSynucleinopathiesAlzheimer's diseaseCell biologyPathogenesisAmyloid (mycology)DopaminergicSynucleinDementiaDiseaseDopamineGeneticsMedicinePathologyGeneImmunologyBotanyAlzheimer's disease research and treatmentsParkinson's Disease Mechanisms and TreatmentsGenetics, Aging, and Longevity in Model Organisms
Human amyloid beta and α-synuclein co-expression in neurons impair behavior and recapitulate features for Lewy body dementia in Caenorhabditis elegans | Litcius