AMPK-SIRT1-PGC1α Signal Pathway Influences the Cognitive Function of Aged Rats in Sevoflurane-Induced Anesthesia
Xiaoyu Yang, Qiu-Jun Li, Wenchao Zhang, Shaoqiang Zheng, Zhijun Qu, Xi Yang, Geng Wang
Topics & Concepts
AMPKMorris water navigation taskSevofluraneOxidative stressEndocrinologyAMP-activated protein kinaseProtein kinase AMitochondrionInternal medicineMedicineTUNEL assayChemistryHippocampusPharmacologyPhosphorylationImmunohistochemistryBiochemistryAnesthesia and Neurotoxicity ResearchIntensive Care Unit Cognitive DisordersCancer, Stress, Anesthesia, and Immune Response