Calcium channel blockers lercanidipine and amlodipine inhibit YY1/ERK/TGF-β mediated transcription and sensitize the gastric cancer cells to doxorubicin
Ponmathi Panneerpandian, Divya Bhaskar Rao, Kumaresan Ganesan
Topics & Concepts
AmlodipineLercanidipineMAPK/ERK pathwayPharmacologyDoxorubicinCalcium channelCancer cellCancerChemistryCancer researchCalciumMedicineSignal transductionBiochemistryInternal medicineChemotherapyBlood pressureEstrogen and related hormone effectsPI3K/AKT/mTOR signaling in cancerCoagulation, Bradykinin, Polyphosphates, and Angioedema