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CNS Lymphocytic Vasculitis in a Young Woman With COVID-19 Infection

Garrett Timmons, Torge Rempe, Elizabeth A. Bevins, Vanessa Goodwill, Annalise E. Miner, Arthur Kavanaugh, Michele Ritter, Jennifer Graves

2021Neurology Neuroimmunology & Neuroinflammation22 citationsDOIOpen Access PDF

Abstract

Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been associated with several neurologic manifestations including the development of cerebral lesions resembling CNS vasculitis in elderly patients with severe coronavirus disease 2019 (COVID-19).1,-,4 Here, we report additional evidence for COVID-19–related CNS vasculitis, confirmed by biopsy, in a young healthy patient with otherwise mild COVID-19 infection. A 26-year-old woman experienced 4 days of anosmia, dysgeusia, malaise, and fatigue 6 days after an airplane flight in mid-March 2020. Approximately 2–3 weeks later, she noticed difficulty keeping “flip-flops” on her left foot slowly progressing to dragging …

Topics & Concepts

AnosmiaMedicineVasculitisDysgeusiaCoronavirus disease 2019 (COVID-19)MalaisePneumoniaSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)DermatologyDiseasePediatricsPathologyImmunologyInternal medicineInfectious disease (medical specialty)Adverse effectLong-Term Effects of COVID-19COVID-19 Clinical Research StudiesRetinal and Optic Conditions
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