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Pathogenic TRIO variants associated with neurodevelopmental disorders perturb the molecular regulation of TRIO and axon pathfinding in vivo

Maxime Bonnet, F. Hoffmann-La Roche, Christine Fagotto‐Kaufmann, Gabriella Gazdagh, Iona Truong, Franck Comunale, Sónia Barbosa, Marion Bonhomme, Nicolas Nafati, David Hunt, Monserrat Pons Rodriguez, Ayeshah Chaudhry, Deborah Shears, Marcos Madruga, Fleur Vansenne, Aurore Curie, Andrey V. Kajava, Diana Baralle, Coralie Fassier, Anne Debant, Susanne Schmidt

2023Molecular Psychiatry17 citationsDOIOpen Access PDF

Topics & Concepts

BiologyAxon guidancePhenotypeGeneticsLoss functionZebrafishRAC1NeuroscienceMutationAxonGenotypeGeneSignal transductionCellular transport and secretionRetinal Development and DisordersSignaling Pathways in Disease
Pathogenic TRIO variants associated with neurodevelopmental disorders perturb the molecular regulation of TRIO and axon pathfinding in vivo | Litcius