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Ketamine-propofol (ketofol) in procedural sedation: a narrative review

Eun‐Ji Choi, Cheul-Hong Kim, Ji-Young Yoon, Eun-Jung Kim

2023Journal of Dental Anesthesia and Pain Medicine15 citationsDOIOpen Access PDF

Abstract

Sedation methods for dental treatment are increasingly explored. Recently, ketofol, which is a combination of ketamine and propofol, has been increasingly used because the advantages and disadvantages of propofol and ketamine complement each other and increase their effectiveness. In this review, we discuss the pharmacology of ketamine and propofol, use of ketofol in various clinical situations, and differences in efficacy between ketofol and other sedatives.

Topics & Concepts

KetaminePropofolMedicineSedationAnesthesiaNarrative reviewIntensive care medicineAnesthesia and Sedative AgentsIntensive Care Unit Cognitive DisordersAnesthesia and Neurotoxicity Research
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