Litcius/Paper detail

Multi-site orbital coupling in Ru-based high-entropy alloy-enabled hydroxyl spillover for enhanced peroxidase-like activity

Qi Yang, Jiawei Zhang, Yuxi Tang, Yan Jun Ju, Xuejiao J. Gao, Chaoyang Chu, Huimin Jia, Weiwei He

2025Chemical Science15 citationsDOIOpen Access PDF

Abstract

and fast transfer of adsorbed hydroxyl (*OH, * denotes the adsorbed state) is achieved, resulting in boosted POD-like activity. The POD-like activity of the HEAzyme remained unchanged for 6 months, exhibiting outstanding stability. A multi-channel colorimetric sensor array was developed to specifically identify eight biological antioxidants, especially for the chiral recognition of l-cysteine (l-Cys) and d-cysteine (d-Cys). This study not only provides an effective, multi-site collaborative mechanism for improving POD-like activity and stability but also extends the horizons and perspectives in nanozymes.

Topics & Concepts

SchematicSpillover effectCoupling (piping)ChemistryAlloyPeroxidaseMaterials scienceEngineeringMetallurgyOrganic chemistryEnzymeElectronic engineeringEconomicsMicroeconomicsAdvanced Nanomaterials in CatalysisNanocluster Synthesis and ApplicationsElectrocatalysts for Energy Conversion