Voltammetric Determination of Favipiravir Used as an Antiviral Drug for the Treatment of Covid‐19 at Pencil Graphite Electrode
Teslime Erşan, Didem Giray Dilgin, Elif Kumrulu, Umur Kumrulu, Yusuf Dilgin
Abstract
Abstract This work describes the sensitive voltammetric determination of favipiravir (FAV) based on its reduction for the first time with a low‐cost and disposable pencil graphite electrode (PGE). In addition, the determination of FAV was also performed based on its oxidation. Differential pulse (DP) voltammograms recorded in 0.5 M H 2 SO 4 for the reduction of FAV show that peak currents increase linearly in the range of 1.0 to 600.0 μM with a limit of detection of 0.35 μM. The acceptable recovery values (98.9–106.0 %) obtained from a pharmaceutical tablet, real human urine, and artificial blood serum samples spiked with FAV confirm the high accuracy of the proposed method.