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In vitro and in vivo evaluation of DC-targeting PLGA nanoparticles encapsulating heparanase CD4+ and CD8+ T-cell epitopes for cancer immunotherapy

Xu-Dong Tang, Kui-Lin Lü, Jin Yü, Hanjian Du, Chaoqiang Fan, Lei Chen

2022Cancer Immunology Immunotherapy29 citationsDOIOpen Access PDF

Topics & Concepts

EpitopeCytotoxic T cellCancer immunotherapyImmunogenicityImmunotherapyAntigenT cellCD8ChemistryCancer researchImmune systemIn vitroBiologyImmunologyBiochemistryImmunotherapy and Immune ResponsesGlycosylation and Glycoproteins ResearchRNA Interference and Gene Delivery
In vitro and in vivo evaluation of DC-targeting PLGA nanoparticles encapsulating heparanase CD4+ and CD8+ T-cell epitopes for cancer immunotherapy | Litcius