Amphiphilic block polymer-based self-assembly of high payload nanoparticles for efficient combinatorial chemo-photodynamic therapy
Qisan Ma, Yanna Zhao, Qingran Guan, Yuping Zhao, Huaizhen Zhang, Zhuang Ding, Qingpeng Wang, Yushu Wu, Min Liu, Jun Han
Abstract
anticancer efficiency due to combinational chemo-photodynamic therapy, enhanced cellular uptake effectiveness, and superb intracellular ROS productivity. Besides, the NPs were proved as absent of systemic toxicity. In summary, this nanoparticle delivery system could be hopefully utilized as effective cancer therapy strategy for synergistically exerting combined chemo-photodynamic therapy in clinic.
Topics & Concepts
Photodynamic therapyPhotosensitizerEthylene glycolMaterials scienceIn vivoNanoparticleAmphiphileDrug deliveryNanotechnologyPEG ratioNanocarriersPolymerChemistryCopolymerOrganic chemistryBiologyBiotechnologyEconomicsComposite materialFinanceNanoplatforms for cancer theranosticsPhotodynamic Therapy Research StudiesNanoparticle-Based Drug Delivery