Discovery of 4-(N-dithiobenzyl piperazine)-1,8-naphthalimide as a potent multi-target antitumor agent with good efficacy, limited toxicity, and low resistance
Simin Liang, Gui-Bin Liang, Huiling Wang, Hong Jiang, Xian‐Li Ma, Jian-Hua Wei, Ri-Zhen Huang, Ye Zhang
Topics & Concepts
ChemistryPiperazineToxicityPharmacologyStereochemistryCombinatorial chemistryOrganic chemistryMedicineCancer Mechanisms and TherapyCancer therapeutics and mechanismsEnzyme function and inhibition