LysR Family Regulator LttR Controls Production of Conjugated Linoleic Acid in Lactobacillus plantarum by Directly Activating the <i>cla</i> Operon
Xinxin Liu, Zhiqiang Xiong, Guangqiang Wang, Lifeng Wang, Yongjun Xia, Xin Song, Lianzhong Ai
Abstract
Our work has identified a novel transcriptional regulator, LTTR, that regulates the production of CLA by activating the transcription of cla -dh and cla -dc, essential genes participating in CLA synthesis in Lactobacillus plantarum . This study provides insight into the regulatory mechanism of CLA synthesis and broadens our understanding of the synthesis and regulatory mechanisms of the biosynthesis of CLA.
Topics & Concepts
Conjugated linoleic acidLactobacillus plantarumRegulatorOperonLactobacillusLactobacillus sakeiChemistryFood scienceBiologyBacteriaBiochemistryLactic acidLinoleic acidFermentationGeneticsGeneEscherichia coliFatty acidMicrobial Metabolic Engineering and BioproductionCarbohydrate Chemistry and SynthesisMicrobial Metabolites in Food Biotechnology