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SUMOylation of RNF146 results in Axin degradation and activation of Wnt/β-catenin signaling to promote the progression of hepatocellular carcinoma

Wenjia Li, Qingfang Han, Yuanxin Zhu, Yingshi Zhou, Jingyuan Zhang, Weijun Wu, Yu Li, Long Liu, Yuntan Qiu, Kaishun Hu, Dong Yin

2023Oncogene28 citationsDOI

Topics & Concepts

SUMO proteinBiologyWnt signaling pathwayUbiquitinUbiquitin ligaseCateninCancer researchCell biologyBeta-cateninRegulatorCarcinogenesisSignal transductionBiochemistryCancerGeneticsGeneUbiquitin and proteasome pathwaysRNA modifications and cancerPeptidase Inhibition and Analysis
SUMOylation of RNF146 results in Axin degradation and activation of Wnt/β-catenin signaling to promote the progression of hepatocellular carcinoma | Litcius