Bioactivation of clozapine by mitochondria of the murine heart: Possible cause of cardiotoxicity
Ege Arzuk, Fuat Karakuş, Hi̇lmi̇ Orhan
Topics & Concepts
CardiotoxicityMitochondrionMitochondrial permeability transition poreClozapinePharmacologyChemistryReactive oxygen speciesMetaboliteBiochemistryBiologyToxicityProgrammed cell deathMedicineApoptosisOrganic chemistrySchizophrenia (object-oriented programming)PsychiatryPharmacogenetics and Drug MetabolismMitochondrial Function and PathologyMetabolism and Genetic Disorders