Enhancement of the Transdermal Delivery of Nonsteroidal Anti-inflammatory Drugs Using Liposomes Containing Cationic Surfactants
Darya A. Kuznetsova, Elmira A. Vasilieva, Denis M. Kuznetsov, Oksana A. Lenina, Sergey K. Filippov, K. A. PETROV, L. Ya. Zakharova, Оleg G. Sinyashin
Abstract
. It was found that liposomal DS and KP are effective for relieving rat paw edema. It should be noted that DS-loaded hybrid liposomes demonstrated the highest therapeutic efficacy compared to conventional vesicles.
Topics & Concepts
LiposomeTransdermalChemistryPulmonary surfactantCationic polymerizationChromatographyVesicleCationic liposomeIn vivoKetoprofenPharmacologyBromideDrug carrierDrug deliveryMembraneOrganic chemistryBiochemistryMedicineGenetic enhancementGeneBiologyBiotechnologyAdvancements in Transdermal Drug DeliverySurfactants and Colloidal SystemsLipid Membrane Structure and Behavior