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Radical-Dual-Difunctionalization and Trifluoromethylative Decarboxylation of Two Different Alkenes

Jing Zhao, Renxiang Liu, Cuiping Luo, Luo Yang

2020Organic Letters25 citationsDOI

Abstract

From a single alkene to two different alkenes! A convenient Fe-catalyzed A–D–A–T-type radical-dual-difunctionalization and cross-coupling of two different alkenes to provide chain elongated and trifluoromethylated aromatic alkenes has been developed.

Topics & Concepts

ChemistryDecarboxylationDual (grammatical number)Medicinal chemistryCombinatorial chemistryOrganic chemistryCatalysisArtLiteratureFluorine in Organic ChemistryInorganic Fluorides and Related CompoundsRadical Photochemical Reactions
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