Reversing the negative effect of adenosine A1 receptor-targeted immunometabolism modulation on melanoma by a co-delivery nanomedicine for self-activation of anti-PD-L1 DNAzyme
Jia Guo, Peng Liu, Benliang Wei, Ying Peng, Jinsong Ding, Hailun Zhang, Guanxiong Zhang, Juan Su, Hong Liu, Wenhu Zhou, Xiang Chen
Topics & Concepts
Cancer researchImmunotherapyMelanomaNanomedicineChemistryAdenosineCancer immunotherapyPharmacologyTumor microenvironmentImmune systemMedicineMaterials scienceImmunologyNanotechnologyBiochemistryNanoparticleTumor cellsAdenosine and Purinergic SignalingRNA Interference and Gene DeliveryAdvanced biosensing and bioanalysis techniques