Matrine-induced nephrotoxicity via GSK-3β/nrf2-mediated mitochondria-dependent apoptosis
Tianyang Wang, Jian Zhang, Haokai Wei, Xi Wang, Minjuan Xie, Yinjie Jiang, Jie Zhou
Topics & Concepts
NephrotoxicityOxidative stressPharmacologyChemistryReactive oxygen speciesApoptosisCytochrome cSmall interfering RNAGSK-3Glycogen synthaseBiochemistryMolecular biologyToxicityBiologyKinaseTransfectionEnzymeOrganic chemistryGeneBioactive natural compoundsPlant-derived Lignans Synthesis and BioactivitySynthesis of Organic Compounds