Development of bifunctional anti-PD-L1 antibody MMAE conjugate with cytotoxicity and immunostimulation
Dian Xiao, Longlong Luo, Jiaguo Li, Zhihong Wang, Lianqi Liu, Fei Xie, Jiannan Feng, Xinbo Zhou
Topics & Concepts
AtezolizumabChemistryCytotoxicityImmunoconjugateCancer researchConjugateImmunotherapyProdrugAntibodyPharmacologyIn vitroImmune systemMonoclonal antibodyPembrolizumabMedicineImmunologyBiochemistryMathematical analysisMathematicsCAR-T cell therapy researchCancer Immunotherapy and BiomarkersMonoclonal and Polyclonal Antibodies Research