A peptide-derived strategy for specifically targeting the mitochondria and ER of cancer cells: a new approach in fighting cancer
Yang Sung Sohn, Anat losub-Amir, Alfredo E. Cárdenas, Ola Karmi, Merav Darash Yahana, Tal Gruman, Linda Rowland, Henri‐Baptiste Marjault, Lauren J. Webb, Ron Mittler, Ron Elber, Assaf Friedler, Rachel Nechushtai
Abstract
An effective anti-cancer therapy should exclusively target cancer cells and trigger in them a broad spectrum of cell death pathways that will prevent avoidance.
Topics & Concepts
NecroptosisCancer cellCancerApoptosisMitochondrionPeptideProgrammed cell deathCancer researchCell biologyCellTransmembrane proteinChemistryBiologyBiochemistryReceptorGeneticsPeptidase Inhibition and AnalysisRNA modifications and cancerAntimicrobial Peptides and Activities