Increased thermal stability and catalytic efficiency of 3-ketosteroid Δ1-dehydrogenase5 from Arthrobacter simplex significantly reduces enzyme dosage in prednisone acetate biosynthesis
Rong Zhang, X. G. Luo, Danni Li, Yating Gao, Xizi Chen, Zhu Xi, Zhongliang Zheng
Topics & Concepts
KetosteroidEnzymeChemistryBiosynthesisArthrobacterCatalysisBiochemistryChromatographyIsomeraseSteroid Chemistry and BiochemistryPharmacogenetics and Drug MetabolismHormonal Regulation and Hypertension