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Celiac Disease

Joshua Elliott Rubin, Sheila E. Crowe

2020Annals of Internal Medicine76 citationsDOI

Abstract

Gluten-related disorders, including celiac disease, wheat allergy, and nonceliac gluten sensitivity (NCGS), are increasingly reported worldwide. Celiac disease is caused by an immune-mediated reaction to ingested gluten in genetically susceptible persons. NCGS is largely a diagnosis of exclusion when other causes of symptoms have been ruled out. All patients with celiac disease should be referred to a registered dietitian nutritionist with expertise in celiac disease and a gastroenterologist who specializes in celiac disease and malabsorptive disorders, and they should remain on a strict gluten-free diet indefinitely. This article provides an overview of gluten- and wheat-related disorders.

Topics & Concepts

MedicineGlutenWheat allergyDiseaseInternal medicineGastroenterologyAllergyImmunologyFood allergyPathologyCeliac Disease Research and ManagementMicroscopic ColitisEosinophilic Esophagitis
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